The MED24 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Med24, and THRAP4. This antibody recognizes Human, Mouse, and Rat antigen. The MED24 Antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).Rachez C., Genes Dev. 12:1787-1800(1998).Nagase T., DNA Res. 2:167-174(1995)